Clotrimazole antifungal cream skin#

Available pharmacodynamic / toxicological data in animals have demonstrated secretion of clotrimazole / metabolites in milk.

During pregnancy, treatment should be done with vaginal tablets, since they can be used without the applicator. As a precautionary measure, the use of clotrimazole in the first trimester of pregnancy should be avoided. Animal studies do not show any direct or indirect harmful effects in terms of reproductive toxicity. There is a limited amount of data on the use of clotrimazole in pregnancy. PREGNANCY AND BREASTFEEDING No human studies have been conducted on the effects of clotrimazole on fertility ' however, animal studies have shown no effect of the drug on fertility. Report any suspected adverse reactions via the national reporting system. Gastrointestinal disorders: abdominal pain. Reproductive system and breast disorders: peeling of the genital area, itching, rash, edema, erythema, discomfort, burning, irritation, pelvic pain, vaginal haemorrhage. Immune system disorders: allergic reaction (syncope, hypotension, dyspnoea, urticaria). Since these reactions derive from spontaneous reports from a population of uncertain size, it is not always possible to define their frequency. SIDE EFFECTS The following adverse reactions were identified after the approval of clotrimazole. 100 mg vaginal tablets: lactose monohydrate, corn starch, magnesium stearate, colloidal anhydrous silica, calcium lactate pentahydrate, crospovidone, lactic acid, hypromellose, microcrystalline cellulose.

NAME GYNO-CANESTEN EXCIPIENTS Vaginal cream: sorbitan stearate, polysorbate 60, cetyl palmitate, cetostearyl alcohol, octyldodecanol, benzyl alcohol, purified water. CONTRAINDICATIONS / SECONDARY EFFECT Hypersensitivity 'to the active substance or to any of the excipients. Vaginal tablets: store at a temperature not exceeding 25 degrees C. STORAGE Vaginal cream: this medicine does not require any special storage conditions. PHARMACOTHERAPEUTIC CATEGORY Gynecological antifectives and antiseptics, imidazole derivatives.

Clotrimazole antifungal cream skin#

The cream contains acetostearyl alcohol: it can cause local skin reactions (eg contact dermatitis). In this case, it is necessary to interrupt the treatment and adopt suitable therapeutic measures. The use, especially if prolonged, of products for topical use, can give rise to sensitization phenomena. The effect is temporary and occurs only during treatment. The cream can reduce the efficacy and safety of latex-based products, such as condoms and diaphragms, when applied to the genital area (women: lips and areas adjacent to the vulva men: foreskin and glans penis). WARNINGS If the patient has fever (38 degrees C or higher), lower abdominal pain, back pain, foul-smelling vaginal discharge, nausea, vaginal bleeding and / or shoulder pain, she should consult a physician.